CellVessel™ is a braided tubular scaffold. It is made of bioabsorbable multifilament (8-filaments) poly-96L/4D-lactide copolymer fiber. The polymer is medical grade and used widely in clinical, surgical orthopedic applications since 1999.
Diameter of single filament varies between 60-70 μm. The measured tensile force (N) of this structure is 180 - 200 N, percentage of strain 45 – 50 % and Young modulus 850 – 900 MPa.
Poly-96L/4D-lactide copolymer has been tested with various cell types. Further information of the tested cell types is available in literature review.
Use
Scaffdex braided scaffold is made for research purposes, only and it should not be used in any kind of clinical settings.
CellVessel™ scaffolds are available in three diameters, with outer diameters of 1.7, 2.4 and 2.9 mm and they are provided as gamma sterilized. If further sterilization is needed before cell culturing we propose ethylene oxide (EtO) or ethanol rinse to avoid further decreasing of inherent viscosity and strength properties. It is recommended to put CellVessel™ into cell culturing media for 24 hours prior amendment of the cells.
The length of delivered pieces is 100 mm. Should CellVessels be cut into wanted length by the user, we recommend light heat treatment of the ends of the two bigger sizes to avoid the unloading of the structure during testing.
Cutting of CellVessel™ is easy with simple soldering/branding equipment with heated surgical knife tip (kuvat Cutting_of_CellVessel_1.jpg, Cutting_of_CellVessel_2.jpg ja Cutting_of_CellVessel_3.jpg). Cut surface is slightly heated and ends of filament melt together, but tubular structure is well maintained. Smooth plastic handle of the equipment can be wiped with disinfectants. This kind of equipment is available for example in Claes Ohlson net store / Cotech branding kit (http://www.clasohlson.co.uk/Product/Product.aspx?id=80297928) Cotech branding kit. Laittaisin tähän linkin Claes Ohlsonin nettikauppaan (www.clasohlson.co.uk), mutta en tuoteosioon asti, ettei meidän tarvitse päivitellä linkkiä, kun he vekslaavat omaansa.
Linkit Technical specification of CellVessel™ja Literature review: Poly-96L/4D-lactide copolymer